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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL5
All Species:
30
Human Site:
T117
Identified Species:
47.14
UniProt:
Q93034
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93034
NP_003469.2
780
90955
T117
P
F
C
Q
L
E
I
T
L
M
G
K
Q
G
S
Chimpanzee
Pan troglodytes
XP_001137909
721
84087
D98
N
I
K
N
R
L
Q
D
S
A
M
K
L
V
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546540
811
94684
T148
P
F
C
Q
L
E
I
T
L
M
G
K
Q
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V5
780
90956
T117
P
F
C
Q
L
E
V
T
L
L
G
K
Q
S
S
Rat
Rattus norvegicus
Q9JJ31
780
90872
T117
P
F
C
Q
L
E
V
T
L
L
G
K
Q
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508663
779
91022
T116
P
F
C
Q
L
E
I
T
L
M
G
K
Q
G
S
Chicken
Gallus gallus
XP_417163
809
94020
T146
P
F
C
Q
L
E
I
T
L
M
G
K
Q
G
S
Frog
Xenopus laevis
Q6GPF3
768
88937
W109
L
Q
T
L
N
Q
A
W
N
D
H
Q
T
A
M
Zebra Danio
Brachydanio rerio
XP_001922879
780
90814
T117
P
F
S
K
L
E
I
T
L
L
G
N
Q
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
V105
K
A
I
S
G
E
E
V
L
L
S
R
Y
T
K
Honey Bee
Apis mellifera
XP_623958
789
91733
S119
P
F
R
Q
L
E
T
S
L
A
G
K
A
P
S
Nematode Worm
Caenorhab. elegans
Q23639
765
88890
K101
I
L
P
L
P
F
K
K
I
D
E
S
S
R
R
Sea Urchin
Strong. purpuratus
XP_787630
787
91852
A129
P
F
K
P
L
E
T
A
T
G
K
G
S
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
K102
F
K
R
W
S
N
H
K
V
M
V
R
W
L
S
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
T121
V
K
R
W
K
R
F
T
I
G
A
I
F
L
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
95.8
N.A.
98.4
98.7
N.A.
98.8
95.6
27.3
95.1
N.A.
29.7
72.3
51.4
72.9
Protein Similarity:
100
92.4
N.A.
96
N.A.
99.6
99.6
N.A.
99.2
96.1
50.2
98.3
N.A.
51.2
83.4
69.3
84.5
P-Site Identity:
100
6.6
N.A.
100
N.A.
80
80
N.A.
100
100
0
73.3
N.A.
13.3
60
0
33.3
P-Site Similarity:
100
6.6
N.A.
100
N.A.
93.3
93.3
N.A.
100
100
13.3
86.6
N.A.
26.6
66.6
6.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
7
7
0
14
7
0
7
7
7
% A
% Cys:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
0
14
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
67
7
0
0
0
7
0
0
0
0
% E
% Phe:
7
60
0
0
0
7
7
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
7
0
0
0
0
14
54
7
0
40
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
7
% H
% Ile:
7
7
7
0
0
0
34
0
14
0
0
7
0
0
0
% I
% Lys:
7
14
14
7
7
0
7
14
0
0
7
54
0
0
7
% K
% Leu:
7
7
0
14
60
7
0
0
60
27
0
0
7
14
0
% L
% Met:
0
0
0
0
0
0
0
0
0
34
7
0
0
0
7
% M
% Asn:
7
0
0
7
7
7
0
0
7
0
0
7
0
0
7
% N
% Pro:
60
0
7
7
7
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
7
0
47
0
7
7
0
0
0
0
7
47
0
0
% Q
% Arg:
0
0
20
0
7
7
0
0
0
0
0
14
0
7
7
% R
% Ser:
0
0
7
7
7
0
0
7
7
0
7
7
14
14
60
% S
% Thr:
0
0
7
0
0
0
14
54
7
0
0
0
7
7
0
% T
% Val:
7
0
0
0
0
0
14
7
7
0
7
0
0
7
0
% V
% Trp:
0
0
0
14
0
0
0
7
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _